3EZ3
Crystal Structure of Plasmodium vivax geranylgeranylpyrophosphate synthase PVX_092040 with zoledronate and IPP bound
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Farnesyl pyrophosphate synthase, putative | polymer | 396 | 46215.8 | 4 | UniProt (A5K4U6) Pfam (PF00348) In PDB | Plasmodium vivax | |
2 | A, B, C, D | ZOLEDRONIC ACID | non-polymer | 272.1 | 4 | Chemie (ZOL) | |||
3 | A, B, C, D | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE | non-polymer | 246.1 | 4 | Chemie (IPE) | |||
4 | D, A, B, C | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) | |||
5 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
6 | D, A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
7 | water | water | 18.0 | 561 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 22 - 396 (UniProt: A5K4U6)
PDB | External Database | Details |
---|---|---|
Met 1 | - | expression tag |
Gly 2 | - | expression tag |
Ser 3 | - | expression tag |
Ser 4 | - | expression tag |
His 5 | - | expression tag |
His 6 | - | expression tag |
His 7 | - | expression tag |
His 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
Ser 11 | - | expression tag |
Ser 12 | - | expression tag |
Gly 13 | - | expression tag |
Arg 14 | - | expression tag |
Glu 15 | - | expression tag |
Asn 16 | - | expression tag |
Leu 17 | - | expression tag |
Tyr 18 | - | expression tag |
Phe 19 | - | expression tag |
Gln 20 | - | expression tag |
Gly 21 | - | expression tag |
Met 134 | Thr 113 | SEE REMARK 999 |
Asp 227 | Asn 206 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 184863.0 | |
Non-Polymers* | Number of molecules | 25 |
Total formula weight | 2764.8 | |
All* | Total formula weight | 187627.8 |