3EYH
Crystal structures of JAK1 and JAK2 inhibitor complexes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tyrosine-protein kinase | polymer | 290 | 33489.2 | 1 | UniProt (Q59GQ2) Pfam (PF07714) UniProt (by SIFTS) (P23458) In PDB | Homo sapiens (human) | |
| 2 | A | 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE | non-polymer | 309.3 | 1 | Chemie (IZA) | |||
| 3 | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33489.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 309.3 | |
| All* | Total formula weight | 33798.5 |
