3EYH
Crystal structures of JAK1 and JAK2 inhibitor complexes
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | AUSTRALIAN SYNCHROTRON BEAMLINE MX1 |
Synchrotron site | Australian Synchrotron |
Beamline | MX1 |
Spacegroup name | C 2 2 21 |
Unit cell lengths | 45.000, 88.220, 145.520 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 10.000 - 2.000 |
R-factor | 0.178 |
Rwork | 0.174 |
R-free | 0.23700 |
RMSD bond length | 0.010 |
RMSD bond angle | 1.252 |
Refinement software | REFMAC (5.2.0019) |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 72.740 |
High resolution limit [Å] | 2.000 |
Number of reflections | 19034 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 |