3ET1
Structure of PPARalpha with 3-[5-Methoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-propionic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Peroxisome proliferator-activated receptor alpha | polymer | 291 | 32874.2 | 2 | UniProt (Q07869) Pfam (PF00104) In PDB | Homo sapiens (human) | PPAR-alpha, Nuclear receptor subfamily 1 group C member 1 |
2 | P, Q | Steroid receptor coactivator 1 | polymer | 16 | 1965.3 | 2 | UniProt (Q15788) In PDB | Homo sapiens (human) | NCoA-1, Nuclear receptor coactivator 1, SRC-1, RIP160, Protein Hin-2, Renal carcinoma antigen NY-REN-52 |
3 | A, B | 3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid | non-polymer | 389.4 | 2 | Chemie (ET1) | |||
4 | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A, B: 199 - 468 (UniProt: Q07869)
PDB | External Database | Details |
---|---|---|
Met 178 | - | expression tag |
Gly 179 | - | expression tag |
Ser 180 | - | expression tag |
Ser 181 | - | expression tag |
His 182 | - | expression tag |
His 183 | - | expression tag |
His 184 | - | expression tag |
His 185 | - | expression tag |
His 186 | - | expression tag |
His 187 | - | expression tag |
Ser 188 | - | expression tag |
Ser 189 | - | expression tag |
Gly 190 | - | expression tag |
Leu 191 | - | expression tag |
Val 192 | - | expression tag |
Pro 193 | - | expression tag |
Arg 194 | - | expression tag |
Gly 195 | - | expression tag |
Ser 196 | - | expression tag |
His 197 | - | expression tag |
Met 198 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 69679.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 778.8 | |
All* | Total formula weight | 70457.9 |