Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ET1 A 1 |
| Chain | Residue |
| A | HOH15 |
| A | ILE354 |
| A | MET355 |
| A | TYR464 |
| A | ILE272 |
| A | PHE273 |
| A | CYS276 |
| A | GLN277 |
| A | THR279 |
| A | SER280 |
| A | TYR314 |
| A | PHE318 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ET1 B 2 |
| Chain | Residue |
| B | ILE272 |
| B | PHE273 |
| B | CYS276 |
| B | THR279 |
| B | SER280 |
| B | TYR314 |
| B | PHE318 |
| B | ILE354 |
| B | MET355 |
| B | HIS440 |
| B | TYR464 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 258 |
| Details | Region: {"description":"Required for heterodimerization with RXRA"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19116277","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ET1","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Essential for heterodimerization with RXRA"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 227 |
| Details | Domain: {"description":"NR LBD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01189","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Motif: {"description":"LXXLL motif 4"} |
