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3EPI

Structure of Human DNA Polymerase Iota complexed with N2-ethylguanine and incoming TTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase iotapolymer42047027.31UniProt (Q9UNA4)
Pfam (PF00817)
Pfam (PF21999)
Pfam (PF11799)
Homo sapiens (human)RAD30 homolog B, Eta2
2B, C
(B, C)
5'-D(*DTP*DCP*DTP*(2EG)P*DGP*DGP*DGP*DTP*DCP*DCP*DTP*DAP*DGP*DGP*DAP*DCP*DCP*(DOC))-3'polymer185520.62
3D
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
4E
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
5F, G, H
(A, B, C)
waterwater18.069Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight58068.6
Non-Polymers*Number of molecules2
Total formula weight118.0
All*Total formula weight58186.5
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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