3EI4

Structure of the hsDDB1-hsDDB2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E	DNA damage-binding protein 1	polymer	1158	129273.9	3	UniProt (Q16531) Pfam (PF10433) Pfam (PF03178) In PDB	Homo sapiens (Human)	hsDDB1, Damage-specific DNA-binding protein 1, UV-damaged DNA-binding factor, DDB p127 subunit, DNA damage-binding protein a, DDBa, UV-damaged DNA-binding protein 1, UV-DDB 1, Xeroderma pigmentosum group E-complementing protein, XPCe, XPE-binding factor, XPE-BF, HBV X-associated protein 1, XAP-1
2	B, D, F	DNA damage-binding protein 2	polymer	436	49047.1	3	UniProt (Q92466) Pfam (PF00400) In PDB	Homo sapiens (Human)	hsDDB2, Damage-specific DNA-binding protein 2, DDB p48 subunit, DDBb, UV-damaged DNA-binding protein 2, UV-DDB 2

Sequence modifications

A, C, E: 1 - 1140 (UniProt: Q16531)

PDB	External Database	Details
Met -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Arg -10	-	expression tag
Arg -9	-	expression tag
Leu -8	-	expression tag
Val -7	-	expression tag
Pro -6	-	expression tag
Arg -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Arg 0	-	expression tag
Tyr 422	Asp 422	SEE REMARK 999
Asp 898	Glu 898	SEE REMARK 999
Val 899	Leu 899	SEE REMARK 999

B, D, F: 10 - 427 (UniProt: Q92466)

PDB	External Database	Details
Met -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Arg -1	-	expression tag
Arg 0	-	expression tag
Leu 1	-	expression tag
Val 2	-	expression tag
Pro 3	-	expression tag
Arg 4	-	expression tag
Gly 5	-	expression tag
Ser 6	-	expression tag
Gly 7	-	expression tag
Gly 8	-	expression tag
Arg 9	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	534963.2
All*	Total formula weight	534963.2

*Water molecules are not included.