3EG5
Crystal structure of MDIA1-TSH GBD-FH3 in complex with CDC42-GMPPNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Cell division control protein 42 homolog | polymer | 178 | 19802.7 | 2 | UniProt (P60766) Pfam (PF00071) | Mus musculus (mouse) | G25K GTP-binding protein |
| 2 | B, D (B, D) | Protein diaphanous homolog 1 | polymer | 383 | 44200.7 | 2 | UniProt (O08808) Pfam (PF06371) Pfam (PF06367) | Mus musculus (mouse) | Diaphanous-related formin-1, DRF1, p140mDIA, mDIA1 |
| 3 | E, G (A, C) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 2 | Chemie (GNP) | |||
| 4 | F, H (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
B, D: 69 - 451 (UniProt: O08808)
| PDB | External Database | Details |
|---|---|---|
| Thr 164 | Asn 164 | engineered mutation |
| Ser 165 | Asn 165 | engineered mutation |
| His 166 | Asn 166 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 128006.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1093.0 | |
| All* | Total formula weight | 129099.8 |
