3ECG
High Resolution HIV-2 Protease Structure in Complex with Antiviral Inhibitor GRL-98065
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 99 | 10728.3 | 2 | UniProt (P04584) Pfam (PF00077) | Human immunodeficiency virus type 2 (ISOLATE ROD) | |
| 2 | C (A) | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(2S,3R)-3-HYDROXY-4-(N-ISOBUTYLBENZO[D][1,3]DIOXOLE-5-SULFONAMIDO)-1-PHENYLBUTAN-2-YLCARBAMATE | non-polymer | 576.7 | 1 | Chemie (065) | |||
| 3 | D, E, O, P, Q... (A, B) | IMIDAZOLE | non-polymer | 69.1 | 6 | Chemie (IMD) | |||
| 4 | F, G, H, I, J... (A, B) | ZINC ION | non-polymer | 65.4 | 11 | Chemie (ZN) | |||
| 5 | AA, BA, CA, DA, K... (B, A) | CHLORIDE ION | non-polymer | 35.5 | 9 | Chemie (CL) | |||
| 6 | N (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | EA, FA (A, B) | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21456.7 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 2052.7 | |
| All* | Total formula weight | 23509.4 |
