3E9S
A new class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Non-structural protein 3 | polymer | 318 | 35726.4 | 1 | UniProt (P0C6U8) Pfam (PF08715) In PDB | SARS coronavirus (SARS-CoV) | nsp3, Papain-like proteinase, PL-PRO, PL2-PRO |
| 2 | A | 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide | non-polymer | 304.4 | 1 | Chemie (TTT) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A: 2 - 316 (UniProt: P0C6U8)
| PDB | External Database | Details |
|---|---|---|
| Ala -1 | - | EXPRESSION TAG |
| Ser 0 | - | EXPRESSION TAG |
| Met 1 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35726.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 440.7 | |
| All* | Total formula weight | 36167.1 |
