3E0V
Crystal structure of pyruvate kinase from Leishmania mexicana in complex with sulphate ions
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Pyruvate kinase | polymer | 539 | 58867.8 | 6 | UniProt (Q27686) Pfam (PF00224) Pfam (PF02887) | Leishmania mexicana | PK |
| 2 | AA, BA, CA, DA, EA... (C, D, A, E, B...) | SULFATE ION | non-polymer | 96.1 | 40 | Chemie (SO4) | |||
| 3 | M, N, QA (A, E) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | AB, BB, CB, XA, YA... (D, E, F, A, B...) | water | water | 18.0 | 314 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 0 - 498 (UniProt: Q27686)
| PDB | External Database | Details |
|---|---|---|
| Met -40 | - | expression tag |
| Gly -39 | - | expression tag |
| Ser -38 | - | expression tag |
| Ser -37 | - | expression tag |
| His -36 | - | expression tag |
| His -35 | - | expression tag |
| His -34 | - | expression tag |
| His -33 | - | expression tag |
| His -32 | - | expression tag |
| His -31 | - | expression tag |
| Ser -30 | - | expression tag |
| Ser -29 | - | expression tag |
| Gly -28 | - | expression tag |
| Leu -27 | - | expression tag |
| Val -26 | - | expression tag |
| Pro -25 | - | expression tag |
| Arg -24 | - | expression tag |
| Gly -23 | - | expression tag |
| Ser -22 | - | expression tag |
| His -21 | - | expression tag |
| Met -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Ser -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| Ser -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Val -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Arg -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Ser 382 | Gly 383 | conflict |
| Tyr 389 | Ser 390 | conflict |
| Arg 404 | Ala 405 | conflict |
| Ser 405 | Gly 406 | conflict |
| Trp 451 | Glu 452 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 353206.6 | |
| Non-Polymers* | Number of molecules | 43 |
| Total formula weight | 4118.8 | |
| All* | Total formula weight | 357325.4 |
