3DRC
INVESTIGATION OF THE FUNCTIONAL ROLE OF TRYPTOPHAN-22 IN ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE BY SITE-DIRECTED MUTAGENESIS
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | DIHYDROFOLATE REDUCTASE | polymer | 159 | 18020.3 | 2 | UniProt (P0ABQ4) Pfam (PF00186) In PDB | Escherichia coli | |
2 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
3 | A, B | METHOTREXATE | non-polymer | 454.4 | 2 | Chemie (MTX) | |||
4 | B | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
5 | water | water | 18.0 | 377 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 159 (UniProt: P0ABQ4)
PDB | External Database | Details |
---|---|---|
Asp 37 | Asn 37 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 36040.7 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1019.9 | |
All* | Total formula weight | 37060.5 |