Side-chain fluorine atoms of non-steroidal vitamin D3 analogs stabilize helix 12 of vitamin D receptor


Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
AVitamin D3 receptor Apolymer30234060.71
UniProt (Q9PTN2)
Pfam (PF00104)
Danio rerio (zebra fish)@PDBjVDR-A, 1,25-dihydroxyvitamin D3 receptor A, Nuclear receptor subfamily 1 group I member 1-A
BSRC-1 (LXXLL motif) from Nuclear receptor coactivator 1polymer151776.11
UniProt (Q15788)
NCoA-1, Steroid receptor coactivator 1, SRC-1, RIP160, Protein Hin-2, Renal carcinoma antigen NY-REN-52
MAGNESIUM IONnon-polymer24.31

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains2
Total molecular weight35836.7
Non-Polymers*Number of molecules2
Total molecular weight506.8
All*Total molecular weight36343.5
*Water molecules are not included.