3DQW
c-Src kinase domain Thr338Ile mutant in complex with ATPgS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Proto-oncogene tyrosine-protein kinase Src | polymer | 286 | 32818.7 | 4 | UniProt (P00523) Pfam (PF07714) | Gallus gallus (chicken) | pp60c-src, p60-Src, c-Src |
| 2 | E, G, I, K (A, B, C, D) | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 4 | Chemie (AGS) | |||
| 3 | F, H, J, L (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 628 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 251 - 533 (UniProt: P00523)
| PDB | External Database | Details |
|---|---|---|
| Gly 248 | - | expression tag |
| His 249 | - | expression tag |
| Met 250 | - | expression tag |
| Ile 338 | Thr 338 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 131274.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2190.2 | |
| All* | Total formula weight | 133464.9 |
