Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004713 | molecular_function | protein tyrosine kinase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
C | 0004672 | molecular_function | protein kinase activity |
C | 0004713 | molecular_function | protein tyrosine kinase activity |
C | 0005524 | molecular_function | ATP binding |
C | 0006468 | biological_process | protein phosphorylation |
D | 0004672 | molecular_function | protein kinase activity |
D | 0004713 | molecular_function | protein tyrosine kinase activity |
D | 0005524 | molecular_function | ATP binding |
D | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG A 1 |
Chain | Residue |
A | ASN391 |
A | ASP404 |
A | AGS534 |
A | HOH717 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MG B 2 |
Chain | Residue |
B | ALA390 |
B | ASN391 |
B | AGS534 |
site_id | AC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG C 3 |
Chain | Residue |
C | ASN391 |
C | AGS534 |
site_id | AC4 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG D 4 |
Chain | Residue |
D | ASN391 |
D | AGS534 |
site_id | AC5 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE AGS A 534 |
Chain | Residue |
A | MG1 |
A | VAL281 |
A | ALA293 |
A | LYS295 |
A | ILE338 |
A | GLU339 |
A | MET341 |
A | SER345 |
A | ASP386 |
A | ASN391 |
A | LEU393 |
A | ASP404 |
A | HOH581 |
A | HOH631 |
A | HOH659 |
A | HOH661 |
A | HOH703 |
A | HOH717 |
site_id | AC6 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE AGS B 534 |
Chain | Residue |
B | MG2 |
B | VAL281 |
B | ALA293 |
B | LYS295 |
B | GLU310 |
B | ILE338 |
B | GLU339 |
B | MET341 |
B | SER345 |
B | ASN391 |
B | LEU393 |
B | ASP404 |
B | GLY406 |
B | HOH594 |
B | HOH699 |
site_id | AC7 |
Number of Residues | 21 |
Details | BINDING SITE FOR RESIDUE AGS C 534 |
Chain | Residue |
C | MG3 |
C | LEU273 |
C | GLY274 |
C | GLY276 |
C | PHE278 |
C | VAL281 |
C | ALA293 |
C | LYS295 |
C | ILE338 |
C | GLU339 |
C | MET341 |
C | SER345 |
C | LEU393 |
C | ASP404 |
C | HOH535 |
C | HOH570 |
C | HOH590 |
C | HOH598 |
C | HOH620 |
C | HOH634 |
C | HOH635 |
site_id | AC8 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE AGS D 534 |
Chain | Residue |
D | MG4 |
D | LEU273 |
D | GLY276 |
D | PHE278 |
D | ALA293 |
D | LYS295 |
D | ILE338 |
D | GLU339 |
D | MET341 |
D | SER345 |
D | LEU393 |
D | ASP404 |
D | HOH543 |
D | HOH560 |
D | HOH573 |
D | HOH619 |
D | HOH624 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 23 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGQGCFGEVWmGtwngttr...........VAIK |
Chain | Residue | Details |
A | LEU273-LYS295 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. YVHrDLRAANILV |
Chain | Residue | Details |
A | TYR382-VAL394 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP386 | |
B | ASP386 | |
C | ASP386 | |
D | ASP386 | |
Chain | Residue | Details |
A | LEU273 | |
B | LEU273 | |
C | LEU273 | |
D | LEU273 | |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | BINDING: |
Chain | Residue | Details |
A | LYS295 | |
B | LYS295 | |
C | LYS295 | |
D | LYS295 | |
Chain | Residue | Details |
A | PTR416 | |
B | PTR416 | |
C | PTR416 | |
D | PTR416 | |
Chain | Residue | Details |
A | TYR436 | |
B | TYR436 | |
C | TYR436 | |
D | TYR436 | |
Chain | Residue | Details |
A | CYS498 | |
B | CYS498 | |
C | CYS498 | |
D | CYS498 | |
Chain | Residue | Details |
A | TYR527 | |
B | TYR527 | |
C | TYR527 | |
D | TYR527 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ASP386 | |
A | ALA390 | |
site_id | CSA10 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
B | ARG388 | |
B | ASN391 | |
B | ASP386 | |
site_id | CSA11 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
C | ARG388 | |
C | ASN391 | |
C | ASP386 | |
site_id | CSA12 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
D | ARG388 | |
D | ASN391 | |
D | ASP386 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
B | ASP386 | |
B | ALA390 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
C | ASP386 | |
C | ALA390 | |
site_id | CSA4 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
D | ASP386 | |
D | ALA390 | |
site_id | CSA5 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ARG388 | |
A | ASP386 | |
site_id | CSA6 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
B | ARG388 | |
B | ASP386 | |
site_id | CSA7 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
C | ARG388 | |
C | ASP386 | |
site_id | CSA8 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
D | ARG388 | |
D | ASP386 | |
site_id | CSA9 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ARG388 | |
A | ASN391 | |
A | ASP386 | |