3DKC
Structure of MET receptor tyrosine kinase in complex with ATP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Hepatocyte growth factor receptor | polymer | 317 | 35750.3 | 1 | UniProt (P08581) Pfam (PF07714) In PDB | Homo sapiens (human) | HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met |
2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
4 | A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
5 | water | water | 18.0 | 333 | Chemie (HOH) |
Sequence modifications
A: 1049 - 1360 (UniProt: P08581)
PDB | External Database | Details |
---|---|---|
Gly 1046 | - | expression tag |
Ser 1047 | - | expression tag |
Leu 1048 | - | expression tag |
Phe 1194 | Tyr 1194 | engineered mutation |
Phe 1234 | Tyr 1234 | engineered mutation |
Asp 1235 | Tyr 1235 | engineered mutation |
Glu 1361 | - | expression tag |
Gly 1362 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35750.3 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 566.9 | |
All* | Total formula weight | 36317.3 |