Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

3DGD

Crystal structure of the F87M/L110M mutant of human transthyretin at pH 4.6

Replaces:  3CYK
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Transthyretinpolymer12713779.44UniProt (P02766)
Pfam (PF00576)
Homo sapiens (human)Prealbumin, TBPA, TTR, ATTR
2AA, BA, CA, DA, E...
(D, A, B, C)
ZINC IONnon-polymer65.415Chemie (ZN)
3EA, FA, GA, H, I...
(D, A, B, C)
ACETATE IONnon-polymer59.012Chemie (ACT)
4HA, R, S
(D, B)
GLYCEROLnon-polymer92.13Chemie (GOL)
5IA, JA, KA, LA
(A, B, C, D)
waterwater18.0374Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 127 (UniProt: P02766)
PDBExternal DatabaseDetails
Met 87Phe 107engineered mutation
Met 110Leu 130engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight55117.7
Non-Polymers*Number of molecules30
Total formula weight1965.9
All*Total formula weight57083.6
*Water molecules are not included.

237423

PDB entries from 2025-06-11

PDB statisticsPDBj update infoContact PDBjnumon