Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001523 | biological_process | retinoid metabolic process |
| A | 0003105 | biological_process | negative regulation of glomerular filtration |
| A | 0005179 | molecular_function | hormone activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006144 | biological_process | purine nucleobase metabolic process |
| A | 0007603 | biological_process | phototransduction, visible light |
| A | 0035578 | cellular_component | azurophil granule lumen |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0140313 | molecular_function | molecular sequestering activity |
| B | 0001523 | biological_process | retinoid metabolic process |
| B | 0003105 | biological_process | negative regulation of glomerular filtration |
| B | 0005179 | molecular_function | hormone activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006144 | biological_process | purine nucleobase metabolic process |
| B | 0007603 | biological_process | phototransduction, visible light |
| B | 0035578 | cellular_component | azurophil granule lumen |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0140313 | molecular_function | molecular sequestering activity |
| C | 0001523 | biological_process | retinoid metabolic process |
| C | 0003105 | biological_process | negative regulation of glomerular filtration |
| C | 0005179 | molecular_function | hormone activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005615 | cellular_component | extracellular space |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006144 | biological_process | purine nucleobase metabolic process |
| C | 0007603 | biological_process | phototransduction, visible light |
| C | 0035578 | cellular_component | azurophil granule lumen |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0070062 | cellular_component | extracellular exosome |
| C | 0140313 | molecular_function | molecular sequestering activity |
| D | 0001523 | biological_process | retinoid metabolic process |
| D | 0003105 | biological_process | negative regulation of glomerular filtration |
| D | 0005179 | molecular_function | hormone activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005576 | cellular_component | extracellular region |
| D | 0005615 | cellular_component | extracellular space |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006144 | biological_process | purine nucleobase metabolic process |
| D | 0007603 | biological_process | phototransduction, visible light |
| D | 0035578 | cellular_component | azurophil granule lumen |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0070062 | cellular_component | extracellular exosome |
| D | 0140313 | molecular_function | molecular sequestering activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN A 128 |
| Chain | Residue |
| A | HIS31 |
| A | ASP74 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN A 129 |
| Chain | Residue |
| A | CYS10 |
| A | HIS56 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 130 |
| Chain | Residue |
| A | HIS88 |
| A | HIS90 |
| A | GLU92 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 131 |
| Chain | Residue |
| A | GLU92 |
| B | TRP41 |
| B | LYS70 |
| B | GLU92 |
| A | TRP41 |
| A | LYS70 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE ACT A 132 |
| Chain | Residue |
| A | THR75 |
| A | TRP79 |
| A | PRO86 |
| A | MET87 |
| A | HIS88 |
| A | HIS90 |
| A | ALA91 |
| A | SER112 |
| A | PRO113 |
| A | TYR116 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN B 128 |
| Chain | Residue |
| B | CYS10 |
| B | HIS56 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN B 129 |
| Chain | Residue |
| B | HIS31 |
| B | ASP74 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 130 |
| Chain | Residue |
| B | HIS88 |
| B | HIS90 |
| B | GLU92 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT B 131 |
| Chain | Residue |
| B | HIS31 |
| B | GLY47 |
| site_id | BC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ACT B 132 |
| Chain | Residue |
| B | THR75 |
| B | TRP79 |
| B | MET87 |
| B | HIS88 |
| B | HIS90 |
| B | ALA91 |
| B | SER112 |
| B | PRO113 |
| B | TYR116 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT B 133 |
| Chain | Residue |
| B | HIS31 |
| B | PRO43 |
| B | PHE44 |
| B | ALA45 |
| B | SER46 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN C 128 |
| Chain | Residue |
| C | HIS88 |
| C | HIS90 |
| C | GLU92 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN C 129 |
| Chain | Residue |
| C | CYS10 |
| C | HIS56 |
| site_id | BC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE ACT C 130 |
| Chain | Residue |
| C | THR75 |
| C | TRP79 |
| C | PRO86 |
| C | MET87 |
| C | HIS88 |
| C | HIS90 |
| C | ALA91 |
| C | SER112 |
| C | PRO113 |
| C | TYR116 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT C 131 |
| Chain | Residue |
| C | PRO86 |
| C | MET87 |
| C | TYR114 |
| D | THR96 |
| D | ASP99 |
| D | TYR105 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT C 132 |
| Chain | Residue |
| C | GLY57 |
| C | LEU58 |
| C | THR59 |
| C | THR60 |
| C | GLU63 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN D 128 |
| Chain | Residue |
| D | HIS31 |
| D | ASP74 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN D 129 |
| Chain | Residue |
| D | CYS10 |
| D | HIS56 |
| site_id | CC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ZN D 130 |
| Chain | Residue |
| D | GLU62 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN D 131 |
| Chain | Residue |
| D | HIS88 |
| D | HIS90 |
| D | GLU92 |
| site_id | CC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ACT D 132 |
| Chain | Residue |
| D | THR75 |
| D | TRP79 |
| D | MET87 |
| D | HIS88 |
| D | HIS90 |
| D | ALA91 |
| D | SER112 |
| D | PRO113 |
| D | TYR116 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT D 133 |
| Chain | Residue |
| D | HIS31 |
| D | PRO43 |
| D | ALA45 |
| D | SER46 |
| site_id | CC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT D 134 |
| Chain | Residue |
| C | LYS35 |
| C | TRP41 |
| D | PHE33 |
| D | TRP41 |
| D | LYS70 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT C 133 |
| Chain | Residue |
| C | LYS70 |
| D | TRP41 |
| D | LYS70 |
| C | TRP41 |
| site_id | CC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ZN A 133 |
| Chain | Residue |
| A | GLU61 |
| site_id | CC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ZN B 134 |
| Chain | Residue |
| B | GLU62 |
| site_id | CC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN C 134 |
| Chain | Residue |
| C | HIS31 |
| C | ASP74 |
| site_id | DC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 135 |
| Chain | Residue |
| B | GLU42 |
| B | PHE44 |
| B | GLU63 |
| site_id | DC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 136 |
| Chain | Residue |
| A | ASP39 |
| B | PHE33 |
| B | TRP41 |
| B | LYS70 |
| B | GLU72 |
| site_id | DC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL D 135 |
| Chain | Residue |
| D | HIS31 |
| D | GLY47 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT |
| Chain | Residue | Details |
| A | LYS15 | |
| D | LYS15 | |
| D | GLU54 | |
| D | SER117 | |
| A | GLU54 | |
| A | SER117 | |
| B | LYS15 | |
| B | GLU54 | |
| B | SER117 | |
| C | LYS15 | |
| C | GLU54 | |
| C | SER117 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Sulfocysteine => ECO:0000269|PubMed:17175208, ECO:0007744|PDB:2H4E |
| Chain | Residue | Details |
| A | CYS10 | |
| B | CYS10 | |
| C | CYS10 | |
| D | CYS10 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: 4-carboxyglutamate; in a patient with Moyamoya disease => ECO:0000269|PubMed:18221012 |
| Chain | Residue | Details |
| A | GLU42 | |
| B | GLU42 | |
| C | GLU42 | |
| D | GLU42 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P02767 |
| Chain | Residue | Details |
| A | SER52 | |
| B | SER52 | |
| C | SER52 | |
| D | SER52 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19167329 |
| Chain | Residue | Details |
| A | ASN98 | |
| B | ASN98 | |
| C | ASN98 | |
| D | ASN98 |
