3D94
Crystal structure of the insulin-like growth factor-1 receptor kinase in complex with PQIP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Insulin-like growth factor 1 receptor beta chain | polymer | 301 | 34448.6 | 1 | UniProt (P08069) Pfam (PF07714) In PDB | Homo sapiens (Human) | Insulin-like growth factor I receptor, IGF-I receptor, CD221 antigen |
| 2 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | A | 3-[cis-3-(4-methylpiperazin-1-yl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine | non-polymer | 489.6 | 1 | Chemie (D94) | |||
| 4 | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A: 956 - 1256 (UniProt: P08069)
| PDB | External Database | Details |
|---|---|---|
| Leu 1212 | Phe 1242 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34448.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 529.7 | |
| All* | Total formula weight | 34978.3 |
