3CYY
The crystal structure of ZO-1 PDZ2 in complex with the Cx43 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Tight junction protein ZO-1 | polymer | 92 | 10152.7 | 2 | UniProt (Q07157) Pfam (PF00595) In PDB | Homo sapiens (human) | Zonula occludens protein 1, Zona occludens protein 1, Tight junction protein 1 |
| 2 | C, D | peptide from Gap junction alpha-1 protein | polymer | 9 | 1112.2 | 2 | UniProt (P08050) In PDB | peptide from Connexin-43, Cx43, Gap junction 43 kDa heart protein | |
| 3 | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
A, B: 182 - 273 (UniProt: Q07157)
| PDB | External Database | Details |
|---|---|---|
| Ala 193 | Arg 193 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 22529.8 | |
| All* | Total formula weight | 22529.8 |
