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3COA

Crystal Structure of FoxO1 DBD Bound to IRE DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, D)
DNA (5'-D(*DTP*DGP*DGP*DTP*DTP*DTP*DGP*DTP*DTP*DTP*DTP*DGP*DCP*DTP*DTP*DG)-3')polymer164932.22
2B, D
(B, E)
DNA (5'-D(*DCP*DAP*DAP*DGP*DCP*DAP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DCP*DCP*DA)-3')polymer164862.22
3E, F
(C, F)
Forkhead box protein O1polymer11713153.72UniProt (Q12778)
Pfam (PF00250)
Homo sapiens (Human)Forkhead box protein O1A, Forkhead in rhabdomyosarcoma
4G, H
(C, F)
CALCIUM IONnon-polymer40.12Chemie (CA)
5I, J, K, L, M...
(A, B, D, E, C...)
waterwater18.0207Chemie (HOH)
Sequence modifications
C, F: 151 - 266 (UniProt: Q12778)
PDBExternal DatabaseDetails
Ser 150-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight45896.3
Non-Polymers*Number of molecules2
Total formula weight80.2
All*Total formula weight45976.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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