3CJF
Crystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Vascular endothelial growth factor receptor 2 | polymer | 309 | 35491.9 | 1 | UniProt (P35968) Pfam (PF07714) In PDB | Homo sapiens (human) | VEGFR-2, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, CD309 antigen |
2 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
3 | A | N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine | non-polymer | 406.4 | 1 | Chemie (SAV) | |||
4 | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A: 804 - 937 (UniProt: P35968)
A: 992 - 1166 (UniProt: P35968)
PDB | External Database | Details |
---|---|---|
Asn 833 | Lys 835 | See remark 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35491.9 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 790.7 | |
All* | Total formula weight | 36282.6 |