3CIG
Crystal structure of mouse TLR3 ectodomain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Toll-like receptor 3 | polymer | 697 | 79631.3 | 1 | UniProt (Q99MB1) Pfam (PF13855) Pfam (PF00560) | Mus musculus (house mouse) | CD283 antigen |
| 2 | B, E (B, E) | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G07375KG) | |||
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G28454KX) | |||
| 4 | D, H (D, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | F (F) | beta-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G15228NC) | |||
| 6 | G (G) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G53389HW) | |||
| 7 | I, J, L, M (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 8 | K (A) | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
| 9 | N (A) | water | water | 18.0 | 79 | Chemie (HOH) |
Sequence modifications
A: 27 - 703 (UniProt: Q99MB1)
| PDB | External Database | Details |
|---|---|---|
| Asn 704 | - | expression tag |
| Leu 705 | - | expression tag |
| Tyr 706 | - | expression tag |
| Phe 707 | - | expression tag |
| Gln 708 | - | expression tag |
| Gly 709 | - | expression tag |
| His 710 | - | expression tag |
| His 711 | - | expression tag |
| His 712 | - | expression tag |
| His 713 | - | expression tag |
| His 714 | - | expression tag |
| His 715 | - | expression tag |
| Trp 716 | - | expression tag |
| Ser 717 | - | expression tag |
| His 718 | - | expression tag |
| Pro 719 | - | expression tag |
| Gln 720 | - | expression tag |
| Phe 721 | - | expression tag |
| Glu 722 | - | expression tag |
| Lys 723 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 79631.3 | |
| Branched | Number of molecules | 7 |
| Total formula weight | 3911.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1049.0 | |
| All* | Total formula weight | 84592.0 |
