3CIG

Crystal structure of mouse TLR3 ectodomain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001819	biological_process	positive regulation of cytokine production
A	0002224	biological_process	toll-like receptor signaling pathway
A	0002756	biological_process	MyD88-independent toll-like receptor signaling pathway
A	0003725	molecular_function	double-stranded RNA binding
A	0003824	molecular_function	catalytic activity
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0006955	biological_process	immune response
A	0016021	cellular_component	integral component of membrane
A	0032722	biological_process	positive regulation of chemokine production
A	0034138	biological_process	toll-like receptor 3 signaling pathway
A	0043330	biological_process	response to exogenous dsRNA
A	0045087	biological_process	innate immune response
A	0050729	biological_process	positive regulation of inflammatory response
A	0051607	biological_process	defense response to virus

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN52
A	ASN57
A	ASN124
A	ASN247

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site_id	SWS_FT_FI2
Number of Residues	11
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:18420935

Chain	Residue	Details
A	ASN70
A	ASN662
A	ASN667
A	ASN196
A	ASN252
A	ASN275
A	ASN291
A	ASN398
A	ASN413
A	ASN424
A	ASN507

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