3C5F
Structure of a binary complex of the R517A Pol lambda mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (T, U) | DNA (5'-D(*DCP*DGP*DGP*DCP*DCP*DGP*DTP*DAP*DCP*DTP*DG)-3') | polymer | 11 | 3350.2 | 2 | |||
| 2 | B, E (P, Q) | DNA (5'-D(*DCP*DAP*DGP*DTP*DAP*DC)-3') | polymer | 6 | 1793.2 | 2 | |||
| 3 | C, F (D, E) | DNA (5'-D(P*DGP*DCP*DCP*DG)-3') | polymer | 4 | 1191.8 | 2 | |||
| 4 | G, H (A, B) | DNA polymerase lambda | polymer | 335 | 37393.6 | 2 | UniProt (Q9UGP5) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (Human) | Pol Lambda, DNA polymerase kappa, DNA polymerase beta-2, Pol beta2 |
| 5 | I, J, K, L, M... (A, B) | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
| 6 | O, P, Q, R, S... (T, P, D, U, Q...) | water | water | 18.0 | 639 | Chemie (HOH) |
Sequence modifications
A, B: 242 - 575 (UniProt: Q9UGP5)
| PDB | External Database | Details |
|---|---|---|
| Met 241 | - | expression tag |
| Ala 517 | Arg 517 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 87457.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 137.9 | |
| All* | Total formula weight | 87595.7 |
