3C5C

Crystal structure of human Ras-like, family 12 protein in complex with GDP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	RAS-like protein 12	polymer	187	21430.1	4	UniProt (Q9NYN1) Pfam (PF00071)	Homo sapiens (human)	RAS-like protein Ris
2	E, F, I, J, L... (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	7	Chemie (MG) PubChem (888)
3	G, K, N, Q (A, B, C, D)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	4	Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537)
4	H, O, R (A, C, D)	UNKNOWN ATOM OR ION	non-polymer			3	Chemie (UNX)
5	S, T, U, V (A, B, C, D)	water	water		18.0	223	Chemie (HOH)

Sequence modifications

A, B, C, D: 18 - 186 (UniProt: Q9NYN1)

PDB	External Database	Details
Met 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
Ser 7	-	expression tag
Ser 8	-	expression tag
Gly 9	-	expression tag
Arg 10	-	expression tag
Glu 11	-	expression tag
Asn 12	-	expression tag
Leu 13	-	expression tag
Tyr 14	-	expression tag
Phe 15	-	expression tag
Gln 16	-	expression tag
Gly 17	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	85720.3
Non-Polymers*	Number of molecules	14
	Total formula weight	1942.9
All*	Total formula weight	87663.2

*Water molecules are not included.