3C5C
Crystal structure of human Ras-like, family 12 protein in complex with GDP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005525 | molecular_function | GTP binding |
| B | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| C | 0003924 | molecular_function | GTPase activity |
| C | 0005525 | molecular_function | GTP binding |
| C | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| C | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| D | 0003924 | molecular_function | GTPase activity |
| D | 0005525 | molecular_function | GTP binding |
| D | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| D | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 202 |
| Chain | Residue |
| A | SER34 |
| A | GDP201 |
| A | HOH301 |
| A | HOH302 |
| A | HOH303 |
| A | HOH304 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 203 |
| Chain | Residue |
| A | HOH359 |
| A | ASP55 |
| A | HOH352 |
| A | HOH355 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 202 |
| Chain | Residue |
| B | SER34 |
| B | GDP201 |
| B | HOH301 |
| B | HOH302 |
| B | HOH303 |
| B | HOH304 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG B 203 |
| Chain | Residue |
| B | ASP55 |
| B | HOH370 |
| B | HOH371 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 202 |
| Chain | Residue |
| C | SER34 |
| C | GDP201 |
| C | HOH301 |
| C | HOH302 |
| C | HOH303 |
| C | HOH304 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG C 203 |
| Chain | Residue |
| C | ASP55 |
| C | HOH352 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 202 |
| Chain | Residue |
| D | SER34 |
| D | GDP201 |
| D | HOH301 |
| D | HOH302 |
| D | HOH303 |
| D | HOH304 |
| site_id | AC8 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE GDP A 201 |
| Chain | Residue |
| A | ARG29 |
| A | GLY30 |
| A | ALA31 |
| A | GLY32 |
| A | LYS33 |
| A | SER34 |
| A | ALA35 |
| A | SER47 |
| A | ASN134 |
| A | LYS135 |
| A | ASP137 |
| A | MET138 |
| A | SER164 |
| A | ALA165 |
| A | CYS166 |
| A | MG202 |
| A | HOH301 |
| A | HOH303 |
| A | HOH304 |
| A | HOH308 |
| A | HOH317 |
| A | HOH326 |
| A | HOH353 |
| B | ASN89 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX A 204 |
| Chain | Residue |
| A | ARG142 |
| A | THR145 |
| A | LYS146 |
| site_id | BC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE GDP B 201 |
| Chain | Residue |
| B | ARG28 |
| B | GLY30 |
| B | ALA31 |
| B | GLY32 |
| B | LYS33 |
| B | SER34 |
| B | ALA35 |
| B | SER47 |
| B | ASN134 |
| B | LYS135 |
| B | ASP137 |
| B | MET138 |
| B | SER164 |
| B | ALA165 |
| B | CYS166 |
| B | MG202 |
| B | HOH301 |
| B | HOH304 |
| B | HOH311 |
| B | HOH312 |
| B | HOH333 |
| B | HOH367 |
| site_id | BC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE GDP C 201 |
| Chain | Residue |
| C | HOH304 |
| C | HOH307 |
| C | HOH313 |
| C | HOH326 |
| C | HOH329 |
| C | HOH334 |
| D | ASN89 |
| C | ARG29 |
| C | GLY30 |
| C | ALA31 |
| C | GLY32 |
| C | LYS33 |
| C | SER34 |
| C | ALA35 |
| C | SER47 |
| C | ASN134 |
| C | LYS135 |
| C | ASP137 |
| C | MET138 |
| C | SER164 |
| C | ALA165 |
| C | CYS166 |
| C | MG202 |
| C | HOH301 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX C 204 |
| Chain | Residue |
| C | ARG44 |
| C | PHE45 |
| D | HOH340 |
| site_id | BC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE GDP D 201 |
| Chain | Residue |
| B | ARG44 |
| D | ARG28 |
| D | ARG29 |
| D | GLY30 |
| D | ALA31 |
| D | GLY32 |
| D | LYS33 |
| D | SER34 |
| D | ALA35 |
| D | PHE45 |
| D | SER47 |
| D | ASN134 |
| D | LYS135 |
| D | ASP137 |
| D | MET138 |
| D | SER164 |
| D | ALA165 |
| D | CYS166 |
| D | MG202 |
| D | HOH301 |
| D | HOH303 |
| D | HOH304 |
| D | HOH314 |
| D | HOH319 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE UNX D 203 |
| Chain | Residue |
| D | ASP55 |
| D | PHE156 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| B | LEU78 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| C | LEU78 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| D | LEU78 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| A | GLY30 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| B | GLY30 |
