3C59
Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glucagon-like peptide 1 receptor | polymer | 122 | 14325.8 | 1 | UniProt (P43220) Pfam (PF02793) | Homo sapiens (human) | GLP-1 receptor, GLP-1-R, GLP-1R |
| 2 | B (B) | Exendin-4 | polymer | 31 | 3485.6 | 1 | UniProt (P26349) Pfam (PF00123) | Exenatide | |
| 3 | C (A) | decyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside | non-polymer | 498.6 | 1 | Chemie (10M) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
B: 9 - 39 (UniProt: P26349)
| PDB | External Database | Details |
|---|---|---|
| Mse 21 | Leu 68 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 17811.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 498.6 | |
| All* | Total formula weight | 18310.1 |
