3C59

Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004930	molecular_function	G protein-coupled receptor activity
A	0004967	molecular_function	glucagon receptor activity
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0008528	molecular_function	G protein-coupled peptide receptor activity
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 10M A 1

Chain	Residue
A	ARG43
A	PHE80
A	ASN82
A	HIS99
A	TYR101
A	HOH155
A	HOH222

---

Functional Information from PROSITE/UniProt

site_id	PS00649
Number of Residues	25
Details	G_PROTEIN_RECEP_F2_1 G-protein coupled receptors family 2 signature 1. CnrtFDeya.CWpdGepgsfvnvsCP

Chain	Residue	Details
A	CYS62-PRO86

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Serine amide => ECO:0000269|PubMed:1313797

Chain	Residue	Details
B	SER39

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Interaction with the endogenous ligand GLP-1 => ECO:0000269|PubMed:19861722

Chain	Residue	Details
A	ARG121
A	GLU128

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:22412906

Chain	Residue	Details
A	ASN63
A	ASN82
A	ASN115

---