3C4H
Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor DR2313
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Poly(ADP-ribose) polymerase 3 | polymer | 357 | 39752.1 | 1 | UniProt (Q9Y6F1) Pfam (PF02877) Pfam (PF00644) In PDB | Homo sapiens (human) | PARP-3, NAD(+) ADP-ribosyltransferase 3, Poly[ADP-ribose] synthetase 3, pADPRT-3, hPARP-3, IRT1 |
| 2 | A | 2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one | non-polymer | 182.2 | 1 | Chemie (DRL) | |||
| 3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
A: 178 - 532 (UniProt: Q9Y6F1)
| PDB | External Database | Details |
|---|---|---|
| Ser 176 | - | expression tag |
| Met 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39752.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 260.4 | |
| All* | Total formula weight | 40012.4 |
