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3BJI

Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Proto-oncogene vavpolymer37844489.12UniProt (P15498)
Pfam (PF00621)
Pfam (PF00169)
Pfam (PF00130)
Homo sapiens (Human)
2C, D
(C, D)
Ras-related C3 botulinum toxin substrate 1 precursorpolymer17719710.82UniProt (P63000)
Pfam (PF00071)
Homo sapiens (Human)p21-Rac1, Ras- like protein TC25, Cell migration-inducing gene 5 protein
3E, F, G, H
(A, B)
ZINC IONnon-polymer65.44Chemie (ZN)
4I, J, K, L
(A, B, C, D)
waterwater18.060Chemie (HOH)
Sequence modifications
A, B: 189 - 565 (UniProt: P15498)
PDBExternal DatabaseDetails
Gly 566-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight128399.7
Non-Polymers*Number of molecules4
Total formula weight261.6
All*Total formula weight128661.3
*Water molecules are not included.

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PDB entries from 2024-11-06

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