3BFT
Structure of the ligand-binding core of GluR2 in complex with the agonist (S)-TDPA at 2.25 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Glutamate receptor 2 | polymer | 263 | 29221.7 | 3 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Rat) | GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2 |
| 2 | D, I, O (A, B, C) | (2S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propanoic acid | non-polymer | 189.2 | 3 | Chemie (S2P) | |||
| 3 | E, F, K, L, M (A, B) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 4 | G, N (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | H (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | J (B) | CACODYLATE ION | non-polymer | 137.0 | 1 | Chemie (CAC) | |||
| 7 | P, Q, R (A, B, C) | water | water | 18.0 | 568 | Chemie (HOH) |
Sequence modifications
A, B, C: 3 - 117 (UniProt: P19491)
A, B, C: 120 - 263 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ala 2 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | linker |
| Thr 119 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 87665.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1113.0 | |
| All* | Total formula weight | 88778.1 |
