3BEJ
Structure of human FXR in complex with MFA-1 and co-activator peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bile acid receptor | polymer | 238 | 27841.0 | 2 | UniProt (Q96RI1) Pfam (PF00104) | Homo sapiens (human) | Farnesoid X-activated receptor, Farnesol receptor HRR-1, Nuclear receptor subfamily 1 group H member 4, Retinoid X receptor-interacting protein 14, RXR-interacting protein 14 |
| 2 | C, D (E, F) | Nuclear receptor coactivator 1 | polymer | 25 | 2806.2 | 2 | UniProt (Q15788) Pfam (PF08832) | Homo sapiens (human) | NCoA-1, Steroid receptor coactivator 1, SRC-1, RIP160, Protein Hin-2, Renal carcinoma antigen NY-REN-52 |
| 3 | E, G (A, B) | YTTRIUM (III) ION | non-polymer | 88.9 | 2 | Chemie (YT3) | |||
| 4 | F, H (A, B) | (8alpha,10alpha,13alpha,17beta)-17-[(4-hydroxyphenyl)carbonyl]androsta-3,5-diene-3-carboxylic acid | non-polymer | 420.5 | 2 | Chemie (MUF) | |||
| 5 | I, J, K, L (A, B, E, F) | water | water | 18.0 | 362 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 61294.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1018.9 | |
| All* | Total formula weight | 62313.2 |
