Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0032052 | molecular_function | bile acid binding |
| A | 0038183 | biological_process | bile acid signaling pathway |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0032052 | molecular_function | bile acid binding |
| B | 0038183 | biological_process | bile acid signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE YT3 A 1 |
| Chain | Residue |
| A | ASP359 |
| A | GLU360 |
| A | HOH474 |
| A | HOH475 |
| A | HOH499 |
| A | HOH514 |
| A | HOH603 |
| B | HOH734 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE YT3 B 2 |
| Chain | Residue |
| B | ASP359 |
| B | GLU360 |
| B | HOH569 |
| B | HOH576 |
| B | HOH590 |
| B | HOH734 |
| B | HOH765 |
| A | HOH603 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE MUF A 473 |
| Chain | Residue |
| A | MET265 |
| A | PHE284 |
| A | LEU287 |
| A | THR288 |
| A | MET290 |
| A | MET328 |
| A | ARG331 |
| A | SER332 |
| A | ILE335 |
| A | LEU348 |
| A | HIS447 |
| A | TRP454 |
| A | PHE461 |
| A | TRP469 |
| A | HOH485 |
| A | HOH508 |
| A | HOH570 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE MUF B 1 |
| Chain | Residue |
| B | MET265 |
| B | PHE284 |
| B | LEU287 |
| B | THR288 |
| B | MET328 |
| B | PHE329 |
| B | ARG331 |
| B | SER332 |
| B | ILE335 |
| B | HIS447 |
| B | MET450 |
| B | TRP454 |
| B | PHE461 |
| B | TRP469 |
| B | HOH595 |
| B | HOH623 |
| B | HOH733 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"6HL1","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by PKC/PRKCZ","evidences":[{"source":"PubMed","id":"18668687","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)","evidences":[{"source":"PubMed","id":"23546875","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Motif: {"description":"LXXLL motif 4"} |
