3B6W
Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686S Mutant in Complex with Glutamate at 1.7 Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutamate receptor 2 | polymer | 263 | 29207.7 | 4 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2 |
| 2 | E, G, I, J (A, B, C) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | F, H (A, B) | GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GLU) | |||
| 4 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 581 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 392 - 506 (UniProt: P19491)
A, B, C, D: 632 - 775 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 390 | - | expression tag |
| Ala 391 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 630 | - | linker |
| Thr 631 | - | linker |
| Ser 686 | Thr 707 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 116830.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 678.5 | |
| All* | Total formula weight | 117509.1 |
