3AM4
A372M mutant of Enoyl-ACP Reductase from Plasmodium falciparum (PfENR) in complex with triclosan variant T1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Enoyl-ACP reductase | polymer | 329 | 37304.3 | 2 | UniProt (Q9BJJ9) Pfam (PF13561) | Plasmodium falciparum | PfENR |
| 2 | C, E (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 3 | D, F (A, B) | 4-(2,4-dichlorophenoxy)-3-hydroxybenzaldehyde | non-polymer | 283.1 | 2 | Chemie (FT1) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 212 | Chemie (HOH) |
Sequence modifications
A, B: 96 - 424 (UniProt: Q9BJJ9)
| PDB | External Database | Details |
|---|---|---|
| Met 372 | Ala 372 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74608.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1893.1 | |
| All* | Total formula weight | 76501.7 |
