3AL6

Crystal structure of Human TYW5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	JmjC domain-containing protein C2orf60	polymer	338	39157.6	4	UniProt (A2RUC4) Pfam (PF13621)	Homo sapiens (human)	hTYW5
2	E, F, H, I (A, B, C, D)	NICKEL (II) ION	non-polymer		58.7	4	Chemie (NI)
3	G, J (B, D)	2-OXOGLUTARIC ACID	non-polymer		146.1	2	Chemie (AKG)

Sequence modifications

A, B, C, D: 1 - 315 (UniProt: A2RUC4)

PDB	External Database	Details
Met -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
Ser -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Glu -8	-	expression tag
Val -7	-	expression tag
Leu -6	-	expression tag
Phe -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Pro -2	-	expression tag
Leu -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	156630.6
Non-Polymers*	Number of molecules	6
	Total formula weight	527.0
All*	Total formula weight	157157.5

*Water molecules are not included.