3AL6
Crystal structure of Human TYW5
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0031591 | biological_process | wybutosine biosynthetic process |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0102524 | molecular_function | tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0031591 | biological_process | wybutosine biosynthetic process |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0102524 | molecular_function | tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity |
| C | 0000049 | molecular_function | tRNA binding |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0031591 | biological_process | wybutosine biosynthetic process |
| C | 0042803 | molecular_function | protein homodimerization activity |
| C | 0102524 | molecular_function | tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity |
| D | 0000049 | molecular_function | tRNA binding |
| D | 0005506 | molecular_function | iron ion binding |
| D | 0005515 | molecular_function | protein binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0031591 | biological_process | wybutosine biosynthetic process |
| D | 0042803 | molecular_function | protein homodimerization activity |
| D | 0102524 | molecular_function | tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NI A 401 |
| Chain | Residue |
| A | HIS160 |
| A | ASP162 |
| A | HIS235 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI B 401 |
| Chain | Residue |
| B | HIS160 |
| B | ASP162 |
| B | HIS235 |
| B | AKG501 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE AKG B 501 |
| Chain | Residue |
| B | LEU157 |
| B | HIS160 |
| B | ASP162 |
| B | ASN166 |
| B | LYS175 |
| B | HIS235 |
| B | VAL237 |
| B | ASN247 |
| B | NI401 |
| B | TYR106 |
| B | ARG149 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NI C 401 |
| Chain | Residue |
| C | HIS160 |
| C | ASP162 |
| C | HIS235 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI D 401 |
| Chain | Residue |
| D | HIS160 |
| D | ASP162 |
| D | HIS235 |
| D | AKG501 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE AKG D 501 |
| Chain | Residue |
| D | TYR106 |
| D | ARG149 |
| D | LEU157 |
| D | HIS160 |
| D | ASP162 |
| D | ASN166 |
| D | LEU168 |
| D | LYS175 |
| D | HIS235 |
| D | VAL237 |
| D | ASN247 |
| D | PHE249 |
| D | NI401 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 495 |
| Details | Domain: {"description":"JmjC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00538","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20972222","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {} |
| Chain | Residue | Details |
