3A4U

Crystal structure of MCFD2 in complex with carbohydrate recognition domain of ERGIC-53

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Protein ERGIC-53	polymer	255	28039.1	1	UniProt (P49257) Pfam (PF03388)	Homo sapiens (human)	ER-Golgi intermediate compartment 53 kDa protein, Lectin mannose-binding 1, Gp58, Intracellular mannose-specific lectin MR60
2	B (B)	Multiple coagulation factor deficiency protein 2	polymer	143	16316.8	1	UniProt (Q8NI22) Pfam (PF13499)	Homo sapiens (human)	MCFD2, Neural stem cell-derived neuronal survival protein
3	C, D, H, I (A, B)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
4	E, F, G, J (A, B)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
5	K, L (A, B)	water	water		18.0	189	Chemie (HOH)

Sequence modifications

B: 27 - 146 (UniProt: Q8NI22)

PDB	External Database	Details
Met 4	-	expression tag
Gly 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
Ser 16	-	expression tag
Ser 17	-	expression tag
Gly 18	-	expression tag
His 19	-	expression tag
Ile 20	-	expression tag
Glu 21	-	expression tag
Gly 22	-	expression tag
Arg 23	-	expression tag
His 24	-	expression tag
Met 25	-	expression tag
Leu 26	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	44355.9
Non-Polymers*	Number of molecules	8
	Total formula weight	528.7
All*	Total formula weight	44884.6

*Water molecules are not included.