37LU
NPC1-NPC2 complex with bis-sterol molecule JM046, pH 5.5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NPC intracellular cholesterol transporter 1 | polymer | 1278 | 142272.9 | 1 | UniProt (O15118) | Homo sapiens (human) | Niemann-Pick C1 protein |
| 2 | B (D) | NPC intracellular cholesterol transporter 2 | polymer | 151 | 16585.2 | 1 | UniProt (P61916) | Homo sapiens (human) | Epididymal secretory protein E1,Human epididymis-specific protein 1,He1,Niemann-Pick disease type C2 protein |
| 3 | C (C) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 4 | D, E, F, G, H... (B, E, G, H, I...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 5 | J, K, L, M, N... (A, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) PubChem (24139) | |||
| 6 | S, U (A, D) | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) PubChem (5997) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 158858.1 | |
| Branched | Number of molecules | 7 |
| Total formula weight | 3132.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2985.4 | |
| All* | Total formula weight | 164976.4 |
