36WL

Mevalonate kinase from Saccharomyces cerevisiae with geranyl pyrophosphate (GPP) bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Mevalonate kinase	polymer	468	51495.4	1	UniProt (P07277)	Saccharomyces cerevisiae (brewer's yeast)	MK,MvK,Ergosterol biosynthesis protein 12,Regulation of autonomous replication protein 1
2	B (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
3	C (A)	GERANYL DIPHOSPHATE	non-polymer		314.2	1	Chemie (GPP)
4	D (A)	D(-)-TARTARIC ACID	non-polymer		150.1	1	Chemie (TAR) PubChem (439655)
5	E (A)	beta-D-glucopyranose	non-polymer		180.2	1	Chemie (BGC) PubChem (64689)
6	F (A)	water	water		18.0	139	Chemie (HOH)

Sequence modifications

A: 1 - 443 (UniProt: P07277)

PDB	External Database	Details
Met -24	-	initiating methionine
Gly -23	-	expression tag
Ser -22	-	expression tag
Ser -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Asp -14	-	expression tag
Tyr -13	-	expression tag
Asp -12	-	expression tag
Ile -11	-	expression tag
Pro -10	-	expression tag
Thr -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	51495.4
Non-Polymers*	Number of molecules	4
	Total formula weight	668.8
All*	Total formula weight	52164.2

*Water molecules are not included.