32JC
Structure of the pathogenic variant T186R of Human SHMT2 in a distorted tetrameric conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine hydroxymethyltransferase, mitochondrial | polymer | 486 | 53865.2 | 2 | UniProt (P34897) | Homo sapiens (human) | SHMT,Glycine hydroxymethyltransferase,Serine methylase |
Sequence modifications
A, B: 22 - 504 (UniProt: P34897)
| PDB | External Database | Details |
|---|---|---|
| Gly 19 | - | expression tag |
| Ser 20 | - | expression tag |
| His 21 | - | expression tag |
| Arg 186 | Thr 186 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 107730.4 | |
| All* | Total formula weight | 107730.4 |
