2ZNO

Human PPAR gamma ligand binding domain in complex with a synthetic agonist TIPP703

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Peroxisome proliferator-activated receptor gamma	polymer	286	32530.7	2	UniProt (P37231) Pfam (PF00104) In PDB	Homo sapiens (human)	PPAR-gamma, Nuclear receptor subfamily 1 group C member 3
2	A, B	(2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}benzyl)butanoic acid	non-polymer		503.7	2	Chemie (S44)
3		water	water		18.0	46	Chemie (HOH)

Sequence modifications

A, B: 195 - 476 (UniProt: P37231)

PDB	External Database	Details
Gly 191	-	expression tag
Ser 192	-	expression tag
His 193	-	expression tag
Met 194	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65061.3
Non-Polymers*	Number of molecules	2
	Total formula weight	1007.3
All*	Total formula weight	66068.6

*Water molecules are not included.