2ZNO
Human PPAR gamma ligand binding domain in complex with a synthetic agonist TIPP703
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Peroxisome proliferator-activated receptor gamma | polymer | 286 | 32530.7 | 2 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (human) | PPAR-gamma, Nuclear receptor subfamily 1 group C member 3 |
2 | A, B | (2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}benzyl)butanoic acid | non-polymer | 503.7 | 2 | Chemie (S44) | |||
3 | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A, B: 195 - 476 (UniProt: P37231)
PDB | External Database | Details |
---|---|---|
Gly 191 | - | expression tag |
Ser 192 | - | expression tag |
His 193 | - | expression tag |
Met 194 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 65061.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1007.3 | |
All* | Total formula weight | 66068.6 |