2ZC5
Penicillin-binding protein 1A (PBP 1A) acyl-enzyme complex (biapenem) from Streptococcus pneumoniae
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Penicillin-binding protein 1A | polymer | 24 | 2639.9 | 2 | UniProt (Q8DR59) UniProt (by SIFTS) (Q04707) In PDB | Streptococcus pneumoniae | PBP-1A, Exported protein 2 |
2 | B, D | Penicillin-binding protein 1A | polymer | 390 | 43566.0 | 2 | UniProt (Q549Y6) Pfam (PF00905) UniProt (by SIFTS) (Q04707) In PDB | Streptococcus pneumoniae | |
3 | B, D | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
4 | B, D | (4R,5S)-3-(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-ylsulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-meth yl-4,5-dihydro-1H-pyrrole-2-carboxylate | non-polymer | 352.4 | 2 | Chemie (BMG) | |||
5 | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
B, D: 264 - 653 (UniProt: Q549Y6)
PDB | External Database | Details |
---|---|---|
Gln 545 | Arg 545 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 92411.8 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 1228.1 | |
All* | Total formula weight | 93639.9 |