2Z3Q

Crystal structure of the IL-15/IL-15Ra complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Interleukin-15	polymer	119	13258.0	2	UniProt (P40933) Pfam (PF02372)	Homo sapiens (human)	IL-15
2	B, D (B, D)	Interleukin-15 receptor alpha chain	polymer	107	11496.1	2	UniProt (Q13261)	Homo sapiens (human)	IL-15R-alpha, IL- 15RA
3	E, F, G, H (A, B, C, D)	water	water		18.0	228	Chemie (HOH)

Sequence modifications

A, C: 1 - 114 (UniProt: P40933)

PDB	External Database	Details
Ala -4	-	expression tag
Met -3	-	expression tag
Ala -2	-	expression tag
Ile -1	-	expression tag
Ser 0	-	expression tag

B, D: 1 - 102 (UniProt: Q13261)

PDB	External Database	Details
Ala -4	-	expression tag
Met -3	-	expression tag
Ala -2	-	expression tag
Ile -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	49508.3
All*	Total formula weight	49508.3

*Water molecules are not included.