2Z0P
Crystal structure of PH domain of Bruton's tyrosine kinase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Tyrosine-protein kinase BTK | polymer | 169 | 19983.0 | 4 | UniProt (Q06187) Pfam (PF00169) Pfam (PF00779) In PDB | Homo sapiens (human) | Bruton tyrosine kinase, Agammaglobulinaemia tyrosine kinase, ATK, B cell progenitor kinase, BPK |
2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
3 | A, B, C, D | (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE | non-polymer | 716.4 | 4 | Chemie (4PT) | |||
4 | water | water | 18.0 | 68 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 79932.1 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 3127.0 | |
All* | Total formula weight | 83059.1 |