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2Z0P

Crystal structure of PH domain of Bruton's tyrosine kinase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DTyrosine-protein kinase BTKpolymer16919983.04UniProt (Q06187)
Pfam (PF00169)
Pfam (PF00779)
In PDB
Homo sapiens (human)Bruton tyrosine kinase, Agammaglobulinaemia tyrosine kinase, ATK, B cell progenitor kinase, BPK
2A, B, C, DZINC IONnon-polymer65.44Chemie (ZN)
3A, B, C, D(2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATEnon-polymer716.44Chemie (4PT)
4waterwater18.068Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight79932.1
Non-Polymers*Number of molecules8
Total formula weight3127.0
All*Total formula weight83059.1
*Water molecules are not included.

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PDB entries from 2024-07-24

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