2YV0

Structural and Thermodynamic Analyses of E. coli ribonuclease HI Variant with Quintuple Thermostabilizing Mutations

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	X	Ribonuclease HI	polymer	155	17560.9	1	UniProt (P0A7Y4) Pfam (PF00075) In PDB	Escherichia coli	RNase HI, Ribonuclease H, RNase H
2		water	water		18.0	217	Chemie (HOH)

Sequence modifications

X: 1 - 155 (UniProt: P0A7Y4)

PDB	External Database	Details
Ala 23	Gly 23	engineered mutation
Pro 62	His 62	engineered mutation
Leu 74	Val 74	engineered mutation
Gly 95	Lys 95	engineered mutation
His 134	Asp 134	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	17560.9
All*	Total formula weight	17560.9

*Water molecules are not included.