2YV0

Structural and Thermodynamic Analyses of E. coli ribonuclease HI Variant with Quintuple Thermostabilizing Mutations

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0000287	molecular_function	magnesium ion binding
X	0003676	molecular_function	nucleic acid binding
X	0004518	molecular_function	nuclease activity
X	0004519	molecular_function	endonuclease activity
X	0004523	molecular_function	RNA-DNA hybrid ribonuclease activity
X	0005515	molecular_function	protein binding
X	0005737	cellular_component	cytoplasm
X	0006401	biological_process	RNA catabolic process
X	0016787	molecular_function	hydrolase activity
X	0043137	biological_process	DNA replication, removal of RNA primer
X	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	141
Details	Domain: {"description":"RNase H type-1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00408","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"1311386","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	6
Details	M-CSA 163

Chain

Residue

Details

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