2YOL
West Nile Virus NS2B-NS3 protease in complex with 3,4- dichlorophenylacetyl-Lys-Lys-GCMA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE PROTEASE SUBUNIT NS2B, SERINE PROTEASE NS3 | polymer | 230 | 24602.4 | 1 | UniProt (P06935) Pfam (PF01002) Pfam (PF00949) | WEST NILE VIRUS | FLAVIVIRIN PROTEASE NS2B REGULATORY SUBUNIT, NON-STRUCTURAL PROTEIN 2B, FLAVIVIRIN PROTEASE NS3 CATALYTIC SUBUNIT, NON-STRUCTURAL PROTEIN 3 |
| 2 | B (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | C (A) | (S)-6-amino-N-((S)-6-amino-1-(((1r,4S)-4-guanidinocyclohexyl)methylamino)-1-oxohexan-2-yl)-2-(2-(3,4-dichlorophenyl)acetamido)hexanamide | non-polymer | 613.6 | 1 | Chemie (EBN) | |||
| 4 | D (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 5 | E (A) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A: 50 - 96 (UniProt: P06935)
A: 1001 - 1170 (UniProt: P06935)
| PDB | External Database | Details |
|---|---|---|
| Gly 46 | - | expression tag |
| Ser 47 | - | expression tag |
| His 48 | - | expression tag |
| Met 49 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 97 | - | linker |
| Gly 98 | - | linker |
| Gly 99 | - | linker |
| Gly 100 | - | linker |
| Ser 101 | - | linker |
| Gly 102 | - | linker |
| Gly 103 | - | linker |
| Gly 104 | - | linker |
| Gly 105 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24602.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 707.8 | |
| All* | Total formula weight | 25310.1 |
