2YMD
Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with serotonin (5-hydroxytryptamine)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | SOLUBLE ACETYLCHOLINE RECEPTOR | polymer | 212 | 24092.9 | 10 | UniProt (Q8WSF8) Pfam (PF02931) | APLYSIA CALIFORNICA (CALIFORNIA SEA HARE) | ACHBP |
| 2 | AA, EA, IA, K, LA... (E, F, G, A, H...) | SEROTONIN | non-polymer | 176.2 | 10 | Chemie (SRO) | |||
| 3 | BA, DA, FA, HA, KA... (E, F, G, A, B...) | GLYCEROL | non-polymer | 92.1 | 14 | Chemie (GOL) | |||
| 4 | CA, GA, JA, M, MA... (E, F, G, A, H...) | PHOSPHATE ION | non-polymer | 95.0 | 10 | Chemie (PO4) | |||
| 5 | AB, BB, SA, TA, UA... (I, J, A, B, C...) | water | water | 18.0 | 2665 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J: 1 - 212 (UniProt: Q8WSF8)
| PDB | External Database | Details |
|---|---|---|
| Val 41 | Ala 60 | conflict |
| Trp 53 | Tyr 72 | engineered mutation |
| Glu 92 | Ser 111 | conflict |
| Val 136 | Ala 155 | conflict |
| Leu 140 | Val 159 | conflict |
| Thr 141 | Lys 160 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 240928.8 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 4001.2 | |
| All* | Total formula weight | 244930.0 |
